cellexus

Extremely low air flow for high quality cells

The CellMaker Low Flow Controller delivers very low air flow, from 0.2 to 2L per minute, for gentle airlift mixing of cells that are more sensitive to shear stress. The results are happier, healthier cells, produced quickly and efficiently.

This system offers pH and dissolved oxygen monitoring and control, as well as temperature control to provide automated optimisation of the culture conditions allowing excellent reproducibility without the labour intensive flask work. With our transparent front panel, you can easily perform visual checks while our system maintains the optimal conditions for your cell culture.

The CellMaker Low Flow bioreactor system has been tested for growth and support of recombinant monoclonal antibody production in the CHO and Hybridoma cell lines. Further tests are ongoing with Jurkat cells and suspension plant cells.

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The CellMaker Regular Controller

The CellMaker range of single-use bioreactors are designed to speed up and simplify cell culture and fermentation processes. Our patented airlift technology delivers a unique way of aerating and mixing your cell culture and fermentation processes, offering a more efficient and faster route to market. Our systems are complete with 21 CFR PART 11 compliant software, accessible through a touchscreen monitor.

The CellMaker Regular Controller allows for manual and automatic control of microbial bioprocesses. Complete your bioreactor with an 8L or 50L Enclosure and our CellMaker Bioreactor Bags.

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The CellMaker Enclosure

The CellMaker bioreactor system is complete with a patented Enclosure which uses unique airlift technology to move cells and nutrients which eliminates the need for mechanical stirring.

For complete control, our self-contained system offers oxygen, pH and temperature regulation, with an integrated Peltier heater cooler enabling accurate temperature control from 16°C to 40°C without the need for external equipment.

Our system is single-use, using disposable CellMaker Bioreactor Bags to culture cells in working volumes from 3L to 50L. Our technology eliminates reactor cleaning and contamination: once your run is complete, simply harvest, remove the bioreactor bag and set up the next process.

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The CellMaker Plus Controller

Using revolutionary airlift technology, the CellMaker single-use bioreactor range delivers fast and efficient bioprocesses. Providing gentle agitation with fully automated control, our system offers a unique method of mixing and aerating your cell culture and fermentation processes. Designed with versatility in mind, this system has been proven in a wide range of fermentation applications used in the life sciences and biopharmaceutical industries. Our systems are complete with 21 CFR PART 11 compliant software, accessible through a touchscreen monitor.

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CellMaker Bioreactor Bags

The specially designed CellMaker Bioreactor Bags have been created to perfectly suit our system and your application. These single-use bags are easily replaced within minutes for a fast turnaround so you can start on your next process.

These sterile bags are fitted into the enclosure and the contents are agitated by bubbles created by a customisable influx of gasses. Our robust system is designed without any moving parts, eliminating the chance of mechanical failure. In addition, gentle agitation from our bubbles reduces the risk of cell shearing usually associated with impellers. Both bags are available in sizes 8L and 50L to suit your enclosure, and provide working volumes of 3L to 8L, and 10L to 50L.

Our CellMaker Regular Bioreactor Bags are compatible for use with our CellMaker Regular Controller and CellMaker Plus Controller. While our CellMaker Plus Bioreactor Bags are designed for use with our CellMaker Plus Controller only. These bags contain a sensor for measuring dissolved oxygen and a pH port making these bags ideal for providing precise control over more challenging processes.

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